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Table 2 Embryology data: fresh embryo transfer

From: Should a single blastocyst transfer policy be a clinical decision or should it depend on the embryological evaluation on day 3?

 

eSET with elective day 5 transfer

eSET with transfer day 3 or 5

Statistical significance

Proportion IVF/ICSI as in vitro fertilization procedure (%)

    

   IVF

44/341 (12.90)

24/247 (9.72)

NS

   ICSI

297/341 (87.10)

223/247 (90.28)

NS

Mean No. cumulus-oocyte complexes (SD)

12.33 (7.23)

11.66 (7.35)

NS

Mean No. metaphase II oocytes

8.50 (6.26)

8.27 (6.46)

NS

Mean No. two pronuclei oocytes

7.46 (5.03)

7.11 (4.95)

NS

Embryos on day 3

2393

16901

-

Embryos on day 5

1619

8162

 

Embryos transferred fresh

309

237

-

Embryo fresh transfer rate (%)

309/1619 (19.09)

237/13903 (17.05)

NS

Subjects with fresh transfer

309

237

-

Subjects fresh transfer rate (%)

309/341 (90.62)

237/249 (95.18)

<0.05

Embryos cryopreserved

640

5604

-

Embryo cryopreservation rate (%)

640/1619 (39.53)

5604/14651 (38.22)

NS

Subjects with cryopreservation

191

1665

-

Subjects cryopreservation rate (%)

191/309 (61.81)

166/237 (70.04)

0.05

  

Day 3

Day 5

 

Proportion IVF/ICSI as in vitro fertilization procedure (%)

    

   IVF

 

12/135 (8.89)

10/102 (9.80)

NS

   ICSI

 

123/135 (91.11)

92/102 (90.20)

NS

Mean No. cumulus-oocyte complexes (SD)

 

9.18 (5.92)

14.52 (6.25)

<0.05

Mean No. metaphase II oocytes (SD)

 

6.00 (4.31)

11.01 (6.08)

<0.05

Mean No. two pronuclei oocytes (SD)

 

4.73 (3.00)

10.05 (4.06)

<0.05

Embryos on day 3

 

615

1000

-

Embryos on day 5

 

NA

775

-

Embryos transferred fresh

 

135

102

-

Embryo fresh transfer rate (%)

 

135/615 (21.95)

102/775 (13.16)

<0.001

Embryos cryopreserved

 

154

363

 

Embryo cryopreservation rate (%)

 

154/615 (25.04)

363/775 (46.84)

<0.001

Subjects with cryopreservation

 

80

84

-

Subjects cryopreservation rate (%)

 

80/135 (59.26)

84/102 (82.35)

<0.001

  1. 1 including 75 day 3 embryos from 6 subjects without fresh transfer.
  2. 2 including 41 day 5 embryos from 2 subjects without fresh transfer.
  3. 3 available day 3 embryos for subjects with fresh day 3 transfer and available day 5 embryos for subjects with fresh day 5 transfer.
  4. 4 including 43 embryo cryopreserved on day 3 and 5 in subjects without fresh transfer.
  5. 5 including 2 subjects with cryopreserved embryos without fresh transfer.