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Table 6 Predicted mean1 relative concentrations of testosterone and oestradiol in women by tertiles of right and left 2D:4D and Δr-l.

From: Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood

  

Right Hand

Left Hand

Δr-l

2D:4D tertile

mean

(95% CI)

P 2 trend

ρ 3

P 4

mean

(95% CI)

P 2 trend

ρ 3

P 4

mean

(95% CI)

P 2 trend

ρ 3

P 4

Testosterone:oestradiol

I

15.0

(13.0 - 16.9)

0.39

-0.03

0.38

14.6

(12.6 - 16.5)

0.56

-0.03

0.52

14.0

(12.1 - 16.0)

0.24

-0.00

0.98

 

II

14.7

(12.8 - 16.6)

   

15.4

(13.4 - 17.3)

   

14.6

(12.6 - 16.5)

   
 

III

14.2

(12.3 - 16.1)

   

14.0

(12.1 - 16.0)

   

15.1

(13.2 - 17.1)

   

Free testosterone:free oestradiol

I

11.4

(9.6 - 13.3)

0.58

-0.04

0.32

11.2

(9.4 - 13.0)

0.68

-0.02

0.60

10.7

(8.8 - 12.5)

0.31

-0.01

0.83

 

II

11.6

(9.7 - 13.4)

   

11.9

(10.1 - 13.7)

   

11.4

(9.6 - 13.3)

   
 

III

10.9

(9.1 - 12.7)

   

10.8

(9.0 - 12.6)

   

11.7

(9.8 - 13.5)

   
  1. 1Estimates from linear mixed models of the ratio of hormone concentrations on 2D:4D tertiles with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, smoking status, previous oral contraceptive and HRT use, parity, duration of lactation, and age at menarche.
  2. 2From likelihood ratio test for linear trend across 2D:4D tertiles.
  3. 3Standardised regression coefficients (correlations) from linear mixed models of the logarithm of hormone concentration on continuous 2D:4D with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, smoking status, previous oral contraceptive and HRT use, parity, duration of lactation, and age at menarche.
  4. 4From likelihood ratio test of ρ.