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Table 5 Predicted mean1 relative concentrations of testosterone and oestradiol in men by tertiles of right and left 2D:4D and Δr-l.

From: Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood

   Right Hand Left Hand Δr-l
2D:4D tertile mean (95% CI) P 2 trend ρ 3 P 4 mean (95% CI) P 2 trend ρ 3 P 4 mean (95% CI) P 2 trend ρ 3 P 4
Testosterone:oestradiol I 160.2 (152.6 - 167.9) 0.03 -0.06 0.03 158.9 (151.3 - 166.5) 0.19 -0.05 0.07 155.7 (148.1 - 163.4) 0.82 -0.01 0.69
  II 154.1 (146.5 - 161.8)     153.4 (145.9 - 160.9)     154.0 (146.4 - 161.7)    
  III 152.1 (144.5 - 159.8)     154.2 (146.6 - 161.7)     156.5 (148.9 - 164.2)    
Free testosterone:free oestradiol I 157.0 (148.6 - 165.4) 0.02 -0.07 0.02 155.4 (147.1 - 163.8) 0.11 -0.06 0.04 151.1 (142.6 - 159.5) 0.92 -0.01 0.64
  II 148.5 (140.1 - 156.9)     147.4 (139.0 - 155.7)     148.3 (139.9 - 156.8)    
  III 146.2 (137.8 - 154.6)     148.1 (139.7 - 156.4)     151.5 (143.0 - 160.0)    
  1. 1Estimates from linear mixed models of the ratio of hormone concentrations on 2D:4D tertiles with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, and smoking status.
  2. 2From likelihood ratio test for linear trend across 2D:4D tertiles.
  3. 3Standardised regression coefficients (correlations) from linear mixed models of the logarithm of hormone concentration on continuous 2D:4D with laboratory batch entered as a random intercept, adjusted for ethnicity, age at blood draw, BMI, and smoking status.
  4. 4From likelihood ratio test of ρ.