Figure 5
From: Myocardial contractility is preserved early but reduced late after ovariectomy in young female rats
Estrogen effects on inotropic stimulus. Effect of estrogen replacement therapy with estradiol valerate on myocardial contractility 60 days after ovariectomy. Estrogen restores inotropic response to extracellular calcium (A) and isoproterenol (B) as well as the rate-isometric force development relationship (C). Force (g/g) values are expressed as mean ± S.E.M. * Ovx n = 8 vs. Sham n = 22, # Ovx vs. Ovx + E2 n = 8, different (P < 0.05) using two-way ANOVA and post hoc Tukey test.