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Table 1 Cell cycle related genes regulated by the depletion of tNASP

From: Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells

Gene name1 Gene Symbol (GenBank)2 Fold change
HeLa cells
Cyclin-dependent kinase inhibitor 1A (p21) CDKN1A (NM_000389) 3.67
Cyclin-dependent kinase 6 CDK6 (NM_001259) 2.69
PC-3 cells
Cyclin D2 CCND2 (NM_001759) 12.45
Cyclin-dependent kinase inhibitor 2A (p16) CDKN1A (NM_000389) 2.87
Beta-2-microglobulin B2M (NM_004048) 2.52
Cyclin G2 CCNG2 (NM_004354) 2.46
Cyclin-dependent kinase inhibitor 1A (p21) CDKN2A (NM_000077) 2.45
Cyclin B2 CCNB2 (NM_004701) 2.4
HUS1checkpoint homolog HUS1(NM_004507) -2.15
Cullin2 CUL2 (NM_003591) -2.6
Cyclin D1 CCND1 (NM_053056) -9.69
PWR-1E
CDC28protein kinase regulatory subunit 2 CKS2 (NM_001827) 4.38
Cyclin-dependent kinase inhibitor 1A (p21) CDKN1A(NM_000389) 2.45
Cyclin G2 CCNG2 (NM_004354) 2.42
Cyclin-dependent kinase inhibitor 1B (p27) CDKN1B (NM_004064) 2.40
Cyclin-dependent kinase 6 CDK6 (NM_001259) 2.25
Cyclin F CCNF (NM_001761) 2.24
Cyclin D2 CCND2 (NM_001759) -2.38
B-cell Cell/lymphoma 2 BCL2 (NM_000633) -2.83
  1. 1 Genes listed present those differentially regulated after HeLa, PC3, RWPE-2, and PWR-1E cells were infected by lentiviral particles containing tNASP shRNA as compared to cells infected with scramble shRNA. The cutoff limit in the analysis was set to two-fold for both induced (+) and repressed (-) genes.
  2. 2 Gene Bank accession number