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Table 3 Significant differently expressed miRNAs exhibiting a fold change ≥ 2 in GD42 and GD75 sheep ovaries and testes, according to real time RT-PCR analysis.

From: Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation

miRNA GPR Score Fold-Change miRNA GPR Score Fold-Change miRNA GPR Score Fold-Change
Significantly higher in GD42 versus GD75 XX gonads Significantly higher in GD75 versus GD42 XX gonads Significantly higher in GD42 versus GD75 XY gonads
miR-22 0.953 1935.53 let-7c 0.883 46.01 miR-302d 0.891 16.36
miR-302d 0.945 119.16 miR-142-5p 0.898 35.40 miR-200c 0.867 11.85
miR-206 0.875 14.76 miR-19b 0.906 27.28 miR-222 0.734 5.32
miR-222 0.875 8.43 miR-19a 0.883 16.43 miR-200b 0.695 4.44
miR-196a 0.844 7.40 miR-135a 0.781 12.28 miR-362 0.609 3.95
miR-328 0.672 7.34 miR-125b 0.883 12.18 miR-99b 0.539 3.95
miR-433 0.781 7.23 let-7a 0.727 10.89 miR-485-5p 0.578 3.61
miR-486 0.813 6.81 miR-130a 0.852 9.93 miR-382 0.586 3.22
miR-216 0.727 6.63 miR-146b 0.648 9.92 miR-149 0.484 3.01
miR-221 0.820 5.88 miR-100 0.883 9.48 miR-15b 0.523 2.82
miR-196b 0.758 5.69 miR-99a 0.859 8.91 miR-92 0.430 2.72
miR-574 0.750 4.83 let-7d 0.453 8.76 miR-17-5p 0.484 2.27
miR-485-5p 0.742 4.52 miR-101 0.688 8.52 miR-107 0.414 2.15
miR-7 0.727 4.45 miR-484 0.750 5.00 Significantly higher in GD75 versus GD42 XY gonads
miR-423 0.617 4.39 miR-150 0.750 4.66 miR-142-3p 0.938 15.89
miR-382 0.680 3.76 miR-30b 0.758 4.41 miR-142-5p 0.938 14.89
miR-134 0.656 3.57 miR-103 0.664 4.32 miR-33 0.922 11.50
miR-181b 0.703 3.54 let-7g 0.664 3.94 miR-211 0.758 6.22
miR-200c 0.625 2.99 miR-497 0.773 3.82 miR-193a 0.633 4.21
miR-668 0.648 2.96 miR-25 0.688 3.71 miR-19b 0.586 3.59
miR-149 0.586 2.90 miR-331 0.664 3.59 miR-19a 0.602 3.53
miR-379 0.672 2.90 miR-143 0.734 3.36 miR-199b 0.539 3.52
miR-598 0.656 2.55 miR-199a 0.695 3.18 miR-27a 0.406 3.35
miR-615 0.430 2.54 miR-33 0.656 2.99 miR-199a 0.414 3.22
miR-214 0.500 2.50 miR-335 0.680 2.89 miR-143 0.453 3.18
miR-539 0.656 2.40 miR-21 0.680 2.84 let-7g 0.563 2.79
miR-652 0.453 2.35 miR-15a 0.648 2.76 miR-22 0.500 2.62
miR-17-5p 0.578 2.31 miR-148a 0.641 2.31 miR-30e-5p 0.500 2.46
miR-15b 0.641 2.27 let-7e 0.492 2.31 miR-204 0.414 2.27
miR-296 0.602 2.21 miR-204 0.563 2.11 miR-30b 0.492 2.25
miR-212 0.539 2.01 miR-148b 0.633 2.08 let-7e 0.430 2.16
  1. Significance (indicated by GPR score) and fold change were determined using Global Pattern Recognition v2.0.