Effects of bone morphogenic protein 4 (BMP4) and its inhibitor, Noggin, on in vitromaturation and culture of bovine preimplantation embryos

Table 4 Oct-4 expression in PA and IVF blastocysts from in vitro maturation experiments

	Treatment	n	Total cells	Oct-4 positive cells	% Oct-4/Total cells
PA	Control	3	194	122	63^b**
	BMP4	2	100	79	79^a
	Noggin	3	240	157	65^b*
IVF	Control	2	136	103	76
	BMP4	3	151	119	79
	Noggin	3	307	218	71

Oct-4 expression in PA and IVF blastocysts produced from oocytes that were matured with 100 ng/ml of either BMP4 or Noggin, Controls were matured without supplementation. Different superscripts indicate statistical differences, 'Difference of proportions test' *p < 0.05; **p < 0.01

ISSN: 1477-7827