Skip to main content
Figure 7 | Reproductive Biology and Endocrinology

Figure 7

From: Modulation of the endocannabinoid system in viable and non-viable first trimester pregnancies by pregnancy-related hormones

Figure 7

The effect of medical abortion and spontaneous miscarriage on the localisation of the endocannabinoid system in first trimester decidua. Images are representative of 60 surgical and 25 medical terminations, and 16 spontaneous miscarriages. Medical termination of pregnancy is characterised by an increase in the expression of CB2 and NAPE-PLD protein whilst overall CB1 expression is decreased and FAAH expression is unaffected. By contrast, spontaneous miscarriage is also characterised by a marked increase in CB2 and FAAH expression and a decrease in CB1 expression that exceeds that of medical termination samples. Images were taken at 200× magnification. Bar = 50 μm. Surgical termination of pregnancy was used as the control condition.

Back to article page