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Table 3 Subgroup analysis of women with BMI ≤25 kg/m2 vs > 25 kg/m2

From: Ovulation induction with minimal dose of follitropin alfa: a case series study

Characteristic/variable

≤25 kg/m2 (n = 217)

> 25 kg/m2 (n = 91)

p value

Age, years

31.6 (3.69)

32.3 (3.7)

NS

BMI, kg/m2

21.5 (2.1)

29.0 (3.3)

0.0001

PCOS, n (%)

131 (60.4)

81 (89.0)

0.0001

Other/unknown etiology, n (%)

84 (38.7)

10 (11.0)

0.0001

Duration of infertility, months

29.0 (3.3)

28.0 (18.8)

NS

Number of previous OI cycles

1.2 (1.2)

1.2 (1.2)

NS

Duration of stimulation, days

10.4 (5.5)

12.5 (4.0)

0.001

Total dose of r-hFSH, IU

574 (417)

606 (356)

0.005

Cycles cancelled, n (%)

11 (5.1)

3 (3.3)

NS

   Poor response, n (%)

8 (3.7)

2 (2.2)

NS

   OHSS risk, n (%)

3 (1.4)

1 (1.1)

NS

Number of follicles ≥16 mm in diameter

1.4 (0.6)

1.4 (0.3)

NS

Clinical pregnancy, * n (%)

54 (24.9)

19 (20.7)

NS

   Singleton pregnancy, n (%)

52 (96.3)

17 (89.5)

NS

   Twin pregnancy, n (%)

2 (3.7)

2 (10.5)

NS

  1. BMI data not recorded in eight cases, so n = 308.
  2. Values are mean (SD) unless otherwise indicated.
  3. *Defined as gestation ≥7 weeks.
  4. BMI, body mass index; NS, not significant; OHSS, ovarian hyperstimulation syndrome; OI, ovulation induction; PCOS, polycystic ovary syndrome; r-hFSH, recombinant human follicle-stimulating hormone; SD, standard deviation.