From: Ovulation induction with minimal dose of follitropin alfa: a case series study
Characteristic/variable | ≤35 years (n = 262) | > 35 years (n = 54) | p value |
---|---|---|---|
Age, years | 30.7 (2.9) | 37.1 (1.1) | 0.0001 |
BMI, kg/m2 | 23.5 (4.7) | 24.6 (3.6) | NS |
PCOS, n (%) | 182 (69.5) | 35 (64.8) | NS |
Other/unknown etiology, n (%) | 80 (30.5) | 19 (35.2) | NS |
Duration of infertility, months | 27.6 (17.9) | 27.8 (21.0) | NS |
Number of previous OI cycles | 1.9 (1.3) | 0.8 (0.8) | 0.02 |
Duration of stimulation, days | 11.1 (5.2) | 10.6 (4.9) | NS |
Total dose of r-hFSH, IU | 525 (425) | 486 (333) | NS |
Cycles cancelled, n (%) | 13 (5.0) | 1 (1.9) | NS |
Poor response, n (%) | 9 (3.4) | 1 (1.9) | NS |
OHSS risk, n (%) | 4 (1.5) | 0 (0) | NS |
Number of follicles ≥16 mm in diameter | 1.3 (0.6) | 1.5 (0.7) | NS |
Clinical pregnancy, * n (%) | 67 (25.6) | 11 (20.4) | NS |
Singleton pregnancy, n (%) | 63 (94.0) | 11 (100) | NS |
Twin pregnancy, n (%) | 4 (6.0) | 0 (0) | NS |