From: Ovulation induction with minimal dose of follitropin alfa: a case series study
Characteristic/variable | All cases (n = 316) |
---|---|
Age, years | 31.8 (3.6) |
BMI, kg/m2 | 23.7 (4.2) |
Etiology | |
PCOS, n (%) | 217 (68.7) |
Other/unknown, n (%) | 99 (31.3) |
Infertility characteristics | |
Duration of infertility, months | 27.8 (18.6) |
Number of previous OI cycles | 1.2 (1.2) |
Ovarian stimulation | |
Starting daily dose, IU | 37.5 (0.0) |
Cycles that completed at 37.5 IU, n (%) | 230 (72.8) |
Cycles that required a dose increase, n (%) | 86 (27.2) |
Final daily dose, IU | 49.9 (24.1) |
Total dose of r-hFSH, IU | 517 (410) |
Duration of stimulation, days | 11.0 (5.1) |
Cycles cancelled, n (%) | 14 (4.4) |
Poor response, n (%) | 10 (3.0) |
Risk of OHSS, n (%) | 4 (1.3) |
Follicular development | |
Number of follicles ≥16 mm in diameter | 1.4 (0.7) |
Cycles resulting in 0 follicles, n (%) | 9 (2.8) |
Cycles resulting in 1 follicle, n (%) | 193 (61.1) |
Cycles resulting in 2 follicles, n (%) | 84 (26.6) |
Cycles resulting in ≥3 follicles, n (%) | 29 (9.2) |
Cycles with no data, n (%) | 1 (0.3) |
OI outcome | |
Clinical pregnancy, * n (%) | 78 (24.7) |
Singleton pregnancy, n (%) | 74 (94.9) |
Twin pregnancy, n (%) | 4 (5.1) |