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Table 2 Comparison of clinical characteristics and treatment outcomes of patients with or without a site-specific hysteroscopic biopsy-induced endometrium injury during the final IVF cycle

From: Site-specific endometrial injury improves implantation and pregnancy in patients with repeated implantation failures

Characteristics Patients with a site-specific endometrium injury (N = 6) Control patients (N = 24) pvaluea
Mean age (yr) 34 ± 3.0 35 ± 4.1 0.58
Weight (kg) 53.4 ± 3.0 54.3 ± 7.4 0.80
FSH (mIU/mL) 6.7 ± 2.3 6.9 ± 2.8 0.86
LH (mIU/mL) 4.2 ± 1.9 4.3 ± 2.1 0.89
Duration of Infertility (yr) 5.7 ± 2.8 6.4 ± 2.9 0.58
Total number of previously transferred embryos 5.0 ± 2.2 7.8 ± 3.0 0.06
Total number of previously IVF/ICSI cycles 2.8 ± 0.8 2.8 ± 0.9 0.88
Length of stimulation (day) 8.7 ± 1.0 9.2 ± 1.1 0.24
Total units of gonadotropin administrated (IU) 1570 ± 377 2206 ± 513 0.01
Endometrium thickness on the day of hCG administration (mm) 10.3 ± 2.0 9.8 ± 2.1 0.62
E2 levels on the day of hCG administration (pg/mL) 1623 ± 550 1822 ± 1078 0.67
Number of oocytes retrieved 11.3 ± 2.9 13.5 ± 7.4 0.50
Number of fertilizations 7.2 ± 4.6 6.3 ± 4.0 0.66
Fertilization rate (%) 59 ± 29 50 ± 22 0.45
Number of all embryos 3.8 ± 2.3 4.8 ± 2.0 0.32
Number of embryos transferred 2.7 ± 1.2 3.0 ± 0.5 0.29
Implantation rate (sac number/transferred embryo) 56% 21% 0.01
Pregnancy rate (clinical pregnancy/per ET) 100% 46% 0.04
Early abortion rate (abortion before 12 wks/total pregnancy) 0% (0/6) 27% (3/11)  
  1. aStudent's t -test of comparisons between control and treatment groups