Reproductive Biology and Endocrinology

Table 6 Transcription factor binding sites (TFBS) over represented in up- and down- regulated genes from CERTL

From: Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivity

Up-regulated genes				Down-regulated genes
Tool for TFBS analysis	Transcription factor name	TFBS matrix	p Value	Tool for TFBS analysis	Transcription factor name	TFBS matrix	p Value
MotifScanner	E47	TRANSFAC	0.008	MotifScanner	E47	TRANSFAC	0.002
	MEF2	TRANSFAC	0.002		SREBP1	TRANSFAC	0.007
	SREBP1	TRANSFAC	0.007		ARNT	TRANSFAC	0.001
TELIS	PBX1	TRANSFAC	0.0001	TELIS	ARNT	TRANSFAC	<0.0001
	AP1	TRANSFAC	0.0005		HNF1	TRANSFAC	0.007
	EVI1	TRANSFAC	0.002		HNF-1	JASPAR	0.007
	SOX5	TRANSFAC	0.003	OTFBS	Hb	TRANSFAC	<0.0001
	Sox-5	JASPAR	0.0031		BR-C Z1	TRANSFAC	<0.0001
	Pbx1	JASPAR	0.007		BR-C Z4	TRANSFAC	0.004
	FREAC-2	JASPAR	0.007		HFH-2	TRANSFAC	<0.0001
	SOX-9	JASPAR	0.008		HFH-3	TRANSFAC	<0.0001
OTFBS	GCN4	TRANSFAC	0.001		FOXJ2	TRANSFAC	<0.0001
	CP2	TRANSFAC	0.007	GATHER	NFY	TRANSFAC	0.004
	Ik-2	TRANSFAC	<0.0001		E2F1	TRANSFAC	0.006
	Bcd	TRANSFAC	<0.0001		DEAF1	TRANSFAC	0.007
	ARP-1	TRANSFAC	<0.0001
	MEF-2	TRANSFAC	0.005
	cap	TRANSFAC	0.004
	E47	TRANSFAC	0.002
	SREBP-1	TRANSFAC	<0.0001
GATHER	SRF	TRANSFAC	0.001
	NRF2	TRANSFAC	0.002
	E2F1	TRANSFAC	0.002
	FREAC2	TRANSFAC	0.003
	HEB	TRANSFAC	0.004
	ELK1	TRANSFAC	0.005

Transcription factors predicted by more than one analysis tool appear in bolded style.

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ISSN: 1477-7827

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