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Table 5 Functional annotation clusters for up- and down-regulated transcripts from CERTL obtained through DAVID webtool

From: Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivity

Database Functional annotation number of genes p Value
up-regulated transcripts
GOTERM_CC_FAT extracellular region 22 <0.0001
SP_PIR_KEYWORDS signal 22 <0.0001
UP_SEQ_FEATURE signal peptide 22 <0.0001
GOTERM_BP_FAT defense response 9 <0.0001
GOTERM_BP_FAT positive regulation of immune response 7 <0.0001
GOTERM_BP_FAT inflammatory response 7 <0.0001
GOTERM_BP_FAT immune effector process 6 <0.0001
GOTERM_BP_FAT complement activation 5 <0.0001
GOTERM_BP_FAT immunoglobulin mediated immune response 5 <0.0001
GOTERM_BP_FAT lymphocyte mediated immunity 5 <0.0001
GOTERM_BP_FAT activation of immune response 5 <0.0001
KEGG_PATHWAY Complement and coagulation cascades 5 <0.0001
SP_PIR_KEYWORDS complement pathway 4 <0.0001
GOTERM_BP_FAT response to steroid hormone stimulus 4 0.0068
GOTERM_BP_FAT cell cycle 7 0.0038
down-regulated transcripts
GOTERM_BP_FAT response to steroid hormone stimulus 4 0.0068
SP_PIR_KEYWORDS cell cycle 6 0.00045
KEGG_PATHWAY cell cycle 4 0.0038
GOTERM_BP_FAT cell division 5 0.0028
GOTERM_BP_FAT cell cycle 7 0.0038
GOTERM_BP_FAT regulation of cell cycle 6 0.00047
SP_PIR_KEYWORDS developmental protein 6 0.0041
UP_SEQ_FEATURE metal ion-binding site:Zinc 1 3 0.0053
  1. Enriched functional annotations found in GATHER (Table 4) and DAVID (table 5) appear in bolded style.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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