Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivity

Table 4 Functional annotation clusters for up- and down-regulated transcripts from CERTL obtained through GATHER webtool

Database	Functional annotation	number of genes	p Value
up-regulated transcripts
Gene Ontology	response to stimulus	16	<0.0001
Gene Ontology	response to biotic stimulus	12	<0.0001
Gene Ontology	defense response	11	<0.0001
Gene Ontology	immune response	10	<0.0001
Gene Ontology	response to stress	9	0.0001
Gene Ontology	complement activation, classical pathway	4	<0.0001
Gene Ontology	complement activation	4	<0.0001
KEGG Pathway	Complement and coagulation cascades	4	0.0002
down-regulated transcripts
Gene Ontology	morphogenesis	10	0.0001
Gene Ontology	cytokinesis	4	0.0001
Gene Ontology	skeletal development	4	0.0001
Gene Ontology	development	12	0.0002
KEGG Pathway	cell cycle	4	0.0002

Enriched functional annotations found in GATHER (Table 4) and DAVID (table 5) appear in bolded style.

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