Figure 1
From: Embryotoxicity assays for leached components from dental restorative materials

Morphologies and development of blastocysts in culture. Morphologies of blastocysts showing normal (A) or degenerated appearance (B) under phase contrast microscope. Note that blastocyst in A is undergoing zona pellucida (ZP) hatching. Normal inner cell mass (ICM) and trophoblast outgrowing (C) scored as +++, when compared with reduced tissue outgrowing (D) occurring in composite-conditioned medium and scored as ++. Magnification approximately 200 × (A, B) and 100 × (C, D).