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Table 3 Comparison of HLA-DRB1 and -DQB1 allele frequencies in patients with familial and sporadic cryptorchidism and in control individuals.

From: Weak association of anti-sperm antibodies and strong association of familial cryptorchidism/infertility with HLA-DRB1polymorphisms in prepubertal Ukrainian boys

Allele HLA-DRB1/D

Controls

N = 60

Cryptorchidism

   

Familial

N = 17

Sporadic

N = 42

p/pc

OR

C.I.

 

%

(N)

%

(N)

%

(N)

   

DRB1* 01

9

(11)

6

(2)

18

(15)

   

DRB1* 15

10

(12)

9

(3)

12

(10)

   

DRB1* 16

6

(7)

3

(1)

5

(4)

   

DRB1* 03

8

(10)

15

(5)

11

(9)

   

DRB1* 04

12

(14)

15

(5)

11

(9)

   

DRB1* 11

10

(12)*

32

(11)*

12

(10)

*0.0012/0.0031

4.304

1.692-10.95

DRB1* 12

3

(4)

6

(2)

1

(1)

   

DR B1*13

15

(18)

6

(2)

12

(10)

   

DR B1*14

5

(6)

3

(1)

2

(2)

   

DRB1* 07

12

(15)

6

(2)

12

(10)

   

DRB1* 08

7

(9)

0

0

2

(2)

   

DRB1* 09

0

(0)

0

0

2

(2)

   

DRB1* 10

2

(2)

0

0

0

0

   

DQB1* 02

18

(22)

18

(6)

21

(18)

   

DQB1* 03

31

(37)

50

(17)

32

(27)

   

DQB1* 04

5

(6)

0

0

0

0

   

DQB1* 05

23

(28)

18

(6)

29

(24)

   

DQB1* 06

22

(27)

15

(5)

18

(15)