Release of a-defensins 1-3 by mDC during pregnancy. (A) Levels of Estradiol measured by ELISA in serum samples from pregnant women (n = 18) during first and third trimester. *p < 0.001 vs first trimester. (B) Levels of a-defensins 1-3 secreted by mDC from all the individual patients (n = 18) at first and third trimester. The data are presented as mean ± SD.