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Table 7 Microarray analysis of apoptosis-associated genes

From: Comparative gene expression profiling of placentas from patients with severe pre-eclampsia and unexplained fetal growth restriction

 

Control

(n = 8)

PE

(n = 8)

Pvalue

TP53 (NM_000546)

8.04 ± 0.10

7.93 ± 0.25

n.s.

MDM2 (NM_002392)

8.96 ± 0.15

8.79 ± 0.20

n.s.

FAS (NM_000043)

6.44 ± 0.19

6.29 ± 0.38

n.s.

FASLG (NM_000639)

5.25 ± 0.09

5.50 ± 0.26

0.030

BCL2 (NM_000633)

8.42 ± 0.16

8.38 ± 0.3

n.s.

MCL1 (NM_021960)

10.07 ± 0.16

10.05 ± 0.27

n.s.

BID (NM_197966)

6.21 ± 0.06

6.21 ± 0.15

n.s.

BAD (NM_004322)

7.16 ± 0.10

7.35 ± 0.25

n.s.

BAK1 (NM_001188)

6.59 ± 0.20

6.51 ± 0.26

n.s.

CASP2 (NM_032982)

7.81 ± 0.07

7.72 ± 0.19

n.s.

CASP3 (NM_004346)

7.22 ± 0.21

7.11 ± 0.25

n.s.

CASP6 (NM_001226)

4.71 ± 0.3

4.77 ± 0.36

n.s.

CASP7 (NM_033338)

7.18 ± 0.10

7.17 ± 0.25

n.s.

CASP8 (NM_001228)

6.75 ± 0.14

6.66 ± 0.22

n.s.

CASP9 (NM_001229)

7.18 ± 0.17

7.18 ± 0.19

n.s.

CASP10 (NM_032977)

5.58 ± 0.14

5.47 ± 0.26

n.s.

XIAP (NM_001167)

7.09 ± 0.23

7.08 ± 0.32

n.s.

BIRC5 (NM_001168)

5.97 ± 0.23

6.07 ± 0.29

n.s.

APAF1 (NM_181861)

6.85 ± 0.11

6.82 ± 0.36

n.s.

P53AIP1 (NM_022112)

4.16 ± 0.14

4.42 ± 0.29

0.025

  1. Data for normalized signal intensities are shown.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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