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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Cadmium suppresses the proliferation of piglet Sertoli cells and causes their DNA damage, cell apoptosis and aberrant ultrastructure

Figure 4

The single-cell gel electrophoresis (comet assay) showed the DNA damage of cadmium chloride on piglet Sertoli cells. A: DNA image of control group A. B: Comet assay revealed that the damaged DNA of cadmium chloride-treated group B contained strand breaks and migrated farther in the gel than intact DNA, creating an image resembling a celestial comet. Scale bars in A and B = 10 μm. C: Quantitation assay showed that DNA damage grades of piglet Sertoli cells by various concentration of cadmium chloride. Compared to control group A, "*" indicated significant difference (p < 0.05), "**" indicated extremely significant difference (p < 0.01).

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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