From: Comparison of estrogens and estrogen metabolites in human breast tissue and urine
ESTROGEN METABOLITES (% of total estrogen) | BREAST TISSUE Mean ± SD | URINE Mean ± SD | P value (Kruskal-Wallis test) |
---|---|---|---|
Estrogens (estrone, 17β-estradiol) | 53.4 ± 19.0 | 20.5 ± 18.4 | 0.02 |
2-Hydroxylation Pathway (*) | 15.6 ± 8.7 | 21.4 ± 10.3 | 0.4 |
16-Hydroxylation Pathway (**) | 30.9 ± 14.7 | 55.4 ± 17.8 | 0.02 |
4-hydroxyestrone ( # ) | -- | 2.7 ± 2.0 | N/A |
2/16 ratio | 0.61 ± 0.5 | 0.47 ± 0.34 | 0.45 |
 | pg/g wet tissue | pg/mL |  |
TOTAL | 348.1 ± 188.8 | 337.4 ± 310.7 | 0.45 |