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Table 5 Comparison of characteristics between endometriosis patients with and without familial clustering

From: Family incidence of endometriosis in first-, second-, and third-degree relatives: case-control study

  patients with a familial incidence (n = 12) patients without a familia incidence (n = 68) P-value
age at onset of endometriosis < 25 years 5/12 (41.7%) 22/68 (32.4%) n.s.*
severe endometriosis (rAFS** IV) 5/12 (41.7%) 16/68 (23.5%) n.s.*
dysmenorrhea 10/12 (83.3%) 56/68 (82.4%) n.s.*
severe dysmenorrhea (V.A.S.*** ≥ 7) 4/12 (33.3%) 16/68 (23.5%) n.s.*
chronic pelvic pain 3/12 (25.0%) 13/68 (19.1%) n.s.*
severe chronic pelvic pain (V.A.S.*** ≥ 7) 4/12 (33.3%) 10/68 (14.7%) n.s.*
infertility 4/12 (33.3%) 39/68 (57.4%) n.s.*
pain on defecation 3/12 (25.0%) 26/68 (38.2%) n.s.*
severe pain on defecation (V.A.S.*** ≥ 7) 8/12 (66.6%) 13/68 (19.1%) n.s.*
dyspareunia 3/12 (25.0%) 10/68 (14.7%) n.s.*
severe dyspareunia
(V.A.S.*** ≥ 7)
4/12 (33.3%) 20/68 (29.4%) n.s.*
  1. * n.s. = not significant
  2. ** rAFS = Revised American Fertility Society classification of endometriosis
  3. *** V.A.S. = Visual analog score