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Table 2 Immunostaining intensity index for MMPs and TIMPs in estrous cycle tissues

From: Ovarian matrix metalloproteinases are differentially regulated during the estrous cycle but not during short photoperiod induced regression in Siberian hamsters (Phodopus sungorus)

  Proestrus Estrus Diestrus I Diestrus II
MMP-2     
Preantral 3.43 (0.8)a 3.08 (0.6) a 2.67 (0.9) a 0.60 (0.5) b
Antral 3.51 (0.3) a 2.96 (0.3) a 0.22 (0.1) b 2.93 (0.7) a
CL N/A 2.70 (0.3) a 2.63 (0.4) a 0.83 (0.2) b
Stroma (CT) 0.65 (0.2) a 0.00 (0.0) b 0.00 (0.0) b 0.00 (0.0) b
Stroma (Steroidogenic) 2.24 (0.2) a 2.25 (0.4) a 2.52 (0.4) a 0.83 (0.2) b
MMP-9     
Preantral 3.83 (0.8) a 3.96 (0.0) a 3.86 (0.1) a 1.67 (0.2) b
Antral 3.57 (0.1) a 3.83 (0.2) a 3.93 (0.1) a 1.33 (0.2) b
CL N/A 3.53 (0.2) a 3.40 (0.3) a 1.25 (0.3) b
Stroma (CT) 0.42 (0.2) 0.17 (0.1) 0.27 (0.1) 0.00 (0.0)
Stroma (Steroidogenic) 2.70 (0.2) a 3.37 (0.2) a 2.93 (0.3) a 0.78 (0.1) b
MMP-14     
Preantral 2.93 (0.4) a 2.63 (0.2) a 3.40 (0.2) a 0.74 (0.3) b
Antral 2.45 (0.2) a 2.56 (0.3) a 2.99 (0.2) a 0.83 (0.4) b
CL N/A 2.67 (0.1) a 3.07 (0.2) a 1.05 (0.3) b
Stroma (CT) 2.14 (0.1) a 2.07 (0.1) a 0.20 (0.1) b 0.53 (0.2) b
Stroma (Steroidogenic) 2.14 (0.1) a 2.10 (0.1) a 2.43 (0.2) a 0.78 (0.2)b
TIMP-1     
Preantral 3.44 (0.1) a 3.22 (0.2) a,b 2.633 (0.3)b 1.97 (0.3) c
Antral 3.19 (0.1) a 3.06 (0.3) a 2.23 (0.1) b 2.00 (0.0) b
CL N/A 2.55 (0.2) 1.98 (0.2) 1.42 (0.4)
Stroma (CT) 0.00 (0.0) 0.00 (0.0) 0.10 (0.1) 0.10 (0.1)
Stroma (Steroidogenic) 2.58 (0.1) a 2.47 (0.2) a 2.13 (0.2) a 0.133 (0.2) b
TIMP-2     
Preantral 3.39 (0.2) a 3.40 (0.2) a 2.80 (0.3) a 0.25 (0.2) b
Antral 3.39 (0.2) a 3.70 (0.1) a 3.60 (0.1) a 0.17 (0.2) b
CL N/A 3.57 (0.1) a 3.13 (0.1) b 0.00 (0.0) c
Stroma (CT) 0.00 (0.0) 0.07 (0.1) 0.00 (0.0) 0.00 (0.0)
Stroma (Steroidogenic) 3.03 (0.3) a 3.87 (0.1) b 3.05 (0.2) a 0.31 (0.2) c
  1. Individual indices presented by ovarian structure type: preantral follicles, antral follicles, corpora lutea (CL), stroma primarily consisting of connective tissue (CT), stroma including potential steroidogenic interstitial glands. Values represented as mean (SEM). Groups with different letters are significantly different (p < 0.05).