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Table 1 Characteristics of donor candidates and donors

From: Can egg donor selection be improved? - a pilot study

 

Candidates

Donors

 

(n = 73)

(n = 21)

Age (years; mean ± SD)

24.2 ± 3.6

24.1 ± 3.5

Total oocyte yield

n/a

17.8 ± 7.2

AMH (ng/mL; mean ± SD)

3.7 ± 2.8

4.2 ± 1.7

   as-AMH normal (% of total1)

3.0 ± 0.7 (37.0)

3.2 ± 0.6 (33.3)

Oocyte yield2

n/a

20.7 ±9.1

low

1.5 ± 0.5 (26.0)

1.8 ± 0.2 (14.3)

Oocyte yield2

n/a

15.7 ± 3.8

high

5.8 ± 2.2 (37.0)

5.4 ± 1.4 (52.4)

Oocyte yield2

n/a

16.5 ± 6.4

FSH (mIU/mL: mean ± SD)

n/a

5.9 ± 2.0

   as-FSH normal (% of total1)

n/a

5.0 ± 1.3 (76.5)

high

n/a

8.5 ± 1.3 (23.5)

FMR1: number of CGG repeats

  

Allele-1

29.1 ± 3.3

29.0 ± 3.2

Allele-2

32.4 ± 2.2

32.2 ± 2.0

   Normal3 n (%)

30 (41.1)

9 (42.9)

AMH (ng/mL; mean ± SD)

3.3 ± 1.6

4.0 ± 1.5

   Heterozygous 3 n (%)

39 (53.4)

12 (57.1)

AMH (ng/mL; mean ± SD)

3.9 ± 2.7

4.0 ± 1.6

Het-norm/low n (%)

15 (20.6)

4 (19.0)

AMH (ng/mL; mean ± SD)

3.3 ± 2.3

3.9 ± 1.2

Het-norm/high n (%)

24 (32.9%)

8 (38.1)

AMH (ng/mL; mean ± SD)

4.4 ± 3.0

4.0 ± 1.9

Homozygous3 n (%)

4 (5.5)

0

   Hom-high/high

2 (2.7)

-

   Hom-low/high

2 (2.7)

-

   Hom-low/low

0

0

  1. The Table summarizes patient characteristics in 73 consecutive egg donor candidates, who after an elimination process (for details see Materials and Methods section) reached a first laboratory testing stage and, from amongst them 21 who reached egg retrieval (one donor did not have FMR1 testing) (donors).
  2. Candidates and donors did not differ statistically in any parameter.
  3. 1 Reflects percentage of patients in total group.
  4. 2 AMH does not distinguish between donors with normal or abnormal yields (p = 0.83).
  5. 3 Normal is defined by both alleles demonstrating between 26-34 CGG repeats; in heterozygous women one allele demonstrates a count outside of this normal range, with het-norm/low defining an abnormally low and het-norm/high and abnormally high count.