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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium

Figure 2

Immune staining of PAFR expression in epithelial cells of fallopian tube fimbria of BRCA1+ patients. (A, B) Immune staining of epithelial cells of fallopian tube fimbria of BRCA1+ patients with and without PAFR antibody. (C, E) Negative PAFR staining on the BRCA1 wild type epithelial cells of fallopian tube fimbria. (D, F) Positive immune staining of PAFR in epithelial cells of fallopian tube fimbria of the BRCA1+ patients. (G) Summary of the intensity scale (mean value with standard error bar) of immune histochemistry staining of the epithelial cells of fallopian tube collected from the patients without (n = 16) and with BRCA1-muation (n = 8) (p < 0.05). The grading system (1-10) of the immune intensity was used for semi-quantification and same set of slides were read by two independent investigators.

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