Table 2 Summary of body weights, estrous cycle and hormonal data for Zucker fa/fa and lean rats

Body weight (g)

lean

80.32 +/- 5.80^c

128.15 +/- 5.30^c

151.61 +/- 8.83^c

171.39 +/- 11.34

fa/fa

108.13 +/- 6.78^a,c

224.36 +/- 4.46^a,c

282.10 +/- 14.61^a,c

340.85 +/- 18.38^a

% of irregular estrous cycle

lean

ND

0 (0/6)

0 (0/6)

0 (0/6)

fa/fa

ND

14.3%(0/6)

28.6% (0/6)

71.4% (0/6)

FSH (ng/ml)

lean

ND

5.07 +/- 0.06

3.01 +/- 0.22

4.63 +/- 0.65

fa/fa

ND

5.15 +/- 0.21

2.87 +/- 0.45

3.81 +/- 0.74

LH (ng/ml)

lean

ND

0.97 +/- 0.23

1.10 +/- 0.14

1.03 +/- 0.18

fa/fa

ND

1.15 +/- 0.57

1.57 +/- 0.18

1.21 +/- 0.23

Estradiol (pg/ml)

lean

ND

13.26 +/- 1.57^d

24.45 +/- 1.41^c

65.51 +/- 18.07

fa/fa

ND

8.53 +/- 0.29^b,d

14.38 +/- 0.98^a

17.70 +/- 1.47^a

Testosterone (ng/ml)

lean

0.16 +/- 0.04^c

0.45 +/- 0.02

0.44 +/- 0.08

0.35 +/- 0.16

fa/fa

0.07 +/- 0.01^c

0.34 +/- 0.12^d

0.28 +/- 0.14^b,d

0.16 +/- 0.05^b

Androstendione (ng/ml)

lean

0.70 +/- 0.35^c

1.50 +/- 0.46

1.55 +/- 0.52

1.35 +/- 0.52

fa/fa

0.13 +/- 0.06^b,c

0.65 +/- 0.12^b,d

0.53 +/- 0.22^a,c

0.33 +/- 0.15^a