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Table 1 Human SIZP mediated induction of acrosome reaction in capacitated human sperm

From: Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida

Treatment Percent induction of acrosomal exocytosis (Mean ± SEM) Statistical significance
Experiment I a   
PBS Control 13.7 ± 1.4  
SIZP (~1 zona) 26.3 ± 1.4 p = 0.003c
SIZP (~2 zonae) 29.4 ± 0.4 p = 0.009c
SIZP (~5 zonae) 39.7 ± 1.7 p = 0.0003c
SIZP (~10 zonae) 36.4 ± 0.9 p = 0.0009c
Experiment II b   
PBS control 14.7 ± 1.3  
PBS + SIZP (~5 zonae) 36.1 ± 3.1 p = 0.007c
Calcium ionophore (10 μM) 56.1 ± 4.5 p = 0.0001c
  1. aSIZP mediated acrosome reaction was studied by employing semen samples from three different donors
  2. bSIZP mediated acrosome reaction was studied by employing semen samples from six different donors
  3. cValues are statistically significant as compared to respective PBS control