Figure 5

pSTAT3 and SOCS3 localisation in endometrial cancer and postmenopausal endometrium. Photomicrographs representing pSTAT3 (A-C) and SOCS3 (D-F) in endometrial cancers. A and D are Tumour Grade 1; B and E are Tumour Grade 2; C and F are Tumour Grade 3; G and H are control postmenopausal endometrium (G shows pSTAT3 and H shows SOCS3). I and J are positive controls for pSTAT3 and SOCS3 respectively showing secretory phase endometrium (insets are negative controls for each). Positive staining shown as brown pigment with blue nuclear counterstain. Negative controls (IgG isotype controls) are shown as insets for pSTAT (G) and SOCS3 (H). Scale bars = 50 μm. (T) tumour epithelial cells, (GE) glandular epithelium and (S) stromal cells