JMR-132 abolished the pro-proliferative and anti-apoptotic effect of EGF. A. Using the MTT assay, it was determined that the growth of SKOV3 and CaOV3 cells was significantly inhibited after continuous treatment with 100 nM JMR-132 for 2 days in combination with EGF (10 μg/ml). Letters (a, b, c) between pairs indicate significant differences (P < 0.05). B. The expression of cleaved caspase3 increased during treatment with 100 nM JMR-132 per day for 2 days in combination with EGF (10 μg/ml). β-actin was used as an internal control. EGF was added 15 min prior to harvesting in (A) and (B).