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Table 2 Ovarian morphological parameters in rats following chemotherapy and pregnancy.

From: Assessment of fertility protection and ovarian reserve with GnRH antagonist in rats undergoing chemotherapy with cyclophosphamide

  Group I
(placebo)
Group II
(CPA)
Group III
(GnRHant + CPA)
Group IV
(GnRHant)
Primordial and primary follicles 3.4 ± 0.53 2.9 ± 0.38 3.8 ± 0.46 3.8 ± 0.52
Preantral follicles 3.0 ± 0.24 3.4 ± 0.54 3.9 ± 0.48 4.1 ± 0.39
Antral follicles 4.4 ± 0.34 5.0 ± 0.60 6.6 ± 0.53 6.4 ± 0.50
Corpora lutea 4.2 ± 0.40 3.3 ± 0.50 3.4 ± 0.40 4.1 ± 0.30
Total number of follicles 10.9 ± 0.70 11.6 ± 1.14 14.3 ± 1.26 17.1 ± 1.22*
Ovarian cross-sectional area (mm2) 5.45 ± 0.50 4.30 ± 0.56 4.56 ± 0.89 4.62 ± 0.66
  1. Data are expressed as mean ± standard error. *p < 0.05 vs. Group I.
  2. CPA, cyclophosphamide; GnRHant, gonadotropin-releasing hormone antagonist (cetrorelix).