|  | Pregnancies after LOD (n = 40) | Pregnancies after CC stimulation (n = 40) | Pregnancies after metformin therapy only (n = 40) | p |
---|---|---|---|---|---|
Age (years)* |  | 27.8 ± 4.9 | 27.5 ± 4.5 | 27.2 ± 4.6 | 0.204 |
Parity | 0 | 38 | 32 | 34 | 0.133 |
 | 1 | 2 | 7 | 6 |  |
 | 2 | 0 | 1 | 0 |  |
Infertility | Prim.+ | 25 | 23 | 26 | 0.781 |
 | Sec.# | 15 | 17 | 14 |  |
BMI (kg/m2) | 26.9 ± 5.0 | 28.0 ± 6.0 | 27.2 ± 5.6 | 0.656 | |
Luteinizing hormone (IU/l)+ | 13.5 ± 4.9 | 14.0 ± 4.2 | 12.2 ± 4.3 | 0.349 | |
Follicle stimulating hormone (IU/l)+ | 5.9 ± 1.8 | 6.1 ± 1.7 | 5.9 ± 1.9 | 0.917 | |
Testosterone (ng/ml)+ | 0.8 ± 0.4 | 0.7 ± 0.3 | 0.8 ± 0.3 | 0.095 | |
Androstendione (ng/ml)+ | 3.7 ± 1.1 | 3.3 ± 1.1 | 3.4 ± 1.1 | 0.143 | |
Pre-existing arterial hypertension (n, %)+ | 4 (10.0%) | 3 (7.5%) | 3 (7.5%) | 0.897 | |
Abnormal oral glucose tolerance test (n, %)+ | 19 (47.5%) | 16 (40.0%) | 18 (45.0%) | 0.789 | |
Duration of metformin therapy (months) | 10.1 ± 2.0 | 6.9 ± 3.1 | 3.4 ± 1.0 | <0.001‡ |