Figure 4
Effect of E 2 BSA on the preovulatory-like surge of LH induced by E 2 . Ewes received an im injection of 60 mg E2BSA 8 h after injection of E2 or saline solution (placebo). Data are presented as the mean ± SEM. Unlike subscripts differ (P < 0.05). (a) E2BSA delayed the interval to the surge, reduced the length of the surge, and decreased the amplitude of the surge induced by E2, regardless the magnitude of the response to E2. (b) E2BSA decreased the mean LH and the AUC (area under the curve of LH) induced by E2, but only in ewes classified as highly responsive to E2.