Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray

Table 6 The up-regulated epididymal genes in the ACH treatment group compared with the control group.

Probe set ID	GenBank NO.	SLR*	Gene symbol	Gene annotations	Gene ontology
1368294_at	NM053907^a	1.4	Dnase1l3	deoxyribonuclease I-like 3	DNA fragmentation during apoptosis
1379794_at	AI029386^a	1.0	Gzmb	granzyme B	Cytolysis, proteolysis, apoptosis
1387011_at	NM130741^a	1.0	Lcn2	lipocalin 2	apoptosis
1388202_at	BI395698^b	3.0	RT1-Aw2	RT1 class Ib, locus Aw2	antigen presentation, MHC class I receptor activity
1370463_x_at	U50449^b	2.5	RT1-CE16	RT1 class I, CE16	antigen presentation, MHC class I receptor activity
1374342_at	BE096652^b	1.8	Ly6g6c	lymphocyte antigen 6 complex	immune response
1388203_x_at	BI395698^b	1.5	RT1-A3	RT1 class I, A3	antigen presentation, endogenous antigen via MHC class I
1385551_at	AW141043^b	1.3	Mcpc	MHC class I protein complex	MHC class I receptor activity
1398390_at	AA892854^b	1.0	LOC498335	Small inducible cytokine B13 precursor	immune response

^a apoptosis-related genes; ^b immune-related genes.
*The "SLR" is fully spelt by "Signal log Ratio", which indicates the log ratio of signal intensity in ACH treated group in relative to that in control group. The expression of the genes listed above in ACH-treated group is up-regulated by 2^SLR times.

ISSN: 1477-7827