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Table 5 The down-regulated epididymal metabolism-related genes from the ACH treatment group compared with the control group.

From: Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray

Probe set ID GenBank NO. SLR* Gene symbol Gene annotations Gene ontology
Gapdhs NM023964 -2.6   glyceraldehyde-3-phosphate dehydrogenase glyceraldehyde-3-phosphate dehydrogenase activity
1397006_at BF401586 -5.5 Prkcb1 Protein kinase C, beta 1 protein kinase C activity, ATP binding
1368561_at NM033352 -1.3 Abcd2 ATP-binding cassette, sub-family D (ALD) ATPase activity, fatty acid metabolism
1383893_at AW140864 -1.0 Atp6v1g3 ATPase ATP hydrolysis coupled proton transport
1391902_at AW527377 -2.7 Pgam2 Phosphoglycerate mutase 2 bisphosphoglycerate phosphatase activity
1368547_at NM130402 -1.5 Ocil osteoclast inhibitory lectin sugar binding
1384837_at AI137672 -1.1 Cd69 CD69 antigen glucose metabolism, lipid metabolism, JAK-STAT cascade, regulation of cholesterol absorption
1387748_at NM013076 -1.1 Lep leptin glucose metabolism, lipid metabolism, fatty acid catabolism, protein binding, JAK-STAT cascade
1380241_at AW435376 -3.4 Lrp5 low density lipoprotein receptor-related protein 5 lipid metabolism
1386964_at NM080775 -1.8 Smgb neonatal submandibular gland protein B lipid binding
1374863_at BI283223 -1.3 RGD1562168 similar to retinoid binding protein 7 lipid binding
1393359_at AW534487 -2.3 Ap3b2 adaptor-related protein complex 3, beta 2 subunit intracellular protein transport
1398695_at BF389056 -5.4 App Amyloid beta (A4) precursor protein protein binding
1368642_at NM031333 -4.4 Cdh2 cadherin 2 protein binding
1387839_at NM012646 -1.7 Cul2 Cullin 2 protein ubiquitination
1367973_at NM031530 -1.2 Ccl2 chemokine (C-C motif) ligand 2 G-protein-coupled receptor binding
1370034_at NP598256 -1.2 Cdc25b cell division cycle 25 homolog B (S. cerevisiae) hydrolase activity
1384190_at BF553848 -1.0 Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 serine-type peptidase activity
  1. *The "SLR", which is fully spelt by "Signal log Ratio", indicates the log ratio of signal intensity in ACH treated group in relative to that in control group. The expressions of the genes listed above in ACH-treated group are down-regulated by 2SLR times.