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Table 1 Stereological measurements, expressed in percentages, obtained from the testicular components of rats of the SC, A, D and AD groups in three different phases of sexual maturation (Mean ± std. dev.)

From: Amifostine reduces the seminiferous epithelium damage in doxorubicin-treated prepubertal rats without improving the fertility status

Group

Volume Density - Vv (%)

 

VvTL

VvEp

VvIT

VvLS

45SC

10.12 ± 1.12

66.64 ± 2.31

8.76 ± 0.89

14.48 ± 2.87

45A

9.02 ± 0.80c

62.38 ± 4.40

7.76 ± 0.78a, c

20.84 ± 4.52 a

45D

11.46 ± 1.19 a, b, d

65.56 ± 2.09

6.64 ± 0.64 a, b

16.34 ± 2.00

45AD

9.40 ± 0.54 c

64.68 ± 1.29

6.64 ± 0.41a

19.26 ± 1.86

60SC

5.38 ± 0.65

64.32 ± 1.37

9.70 ± 0.44

20.74 ± 1.13

60A

7.42 ± 0.47 a, c, d

69.30 ± 1.92 a, c

9.18 ± 0.28 c

14.10 ± 1.98a, c

60D

10.56 ± 1.32 a, b, d

58.22 ± 2.24a, b, d

8.42 ± 0.49a, b

22.80 ± 2.61b, d

60AD

9.28 ± 0.37 a, b, c

70.00 ± 1.52 a, c

8.42 ± 0.75 a

12.50 ± 1.87a, c

90SC

10.82 ± 0.58

65.48 ± 2.33

9.30 ± 0.36

15.16 ± 1.43

90A

11.78 ± 1.07 c, d

65.00 ± 3.21c, d

8.78 ± 0.76 c, d

14.42 ± 3.33d

90D

16.40 ± 1.92a, b, d

57.60 ± 2.35a, b, d

6.80 ± 0.60a, b, d

19.20 ± 2.32d

90AD

8.54 ± 0.52a, b, c

61.70 ± 1.59b, c

7.94 ± 0.51 a, b, c

22.00 ± 2.05 a, b, c

  1. Volume Densities (Vv): Tubular Lumen (VvTL); Seminiferous Epithelium (VvEp);
  2. Interstitial Tissue (VvIT); Lymphatic Space (VvLS)
  3. P < 0.05 (significant): a = significant when compared to SC; b = significant when
  4. compared to A; c = significant when compared to D; d = significant when compared
  5. to AD