Regulatory network analysis. (A) The network is color coded with nodes given in red and blue for transcription factors (TF) showing stronger (up) or weaker (down) signals in the mutant, respectively. Target genes showing stronger or weaker signals in the mutant are given in dark blue (up) and green (down), respectively. The thickness of the edge represents the number of published protein/DNA interactions (see Methods). Sox9 is given in blue. (B) Three examples of small regulatory networks are given. A legend for the color code is shown.