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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress

Figure 2

Gene clustering and GO term analysis. (A) A false-color heatmap shows cases of increasing (up) mRNA signal intensities across the replicates (R1, R2) for different total testis samples (top) at the time points given (bottom). They are compared to four different purified testicular cell types and two external controls (Testis, Ovary). Genes are grouped into three different clusters according to their signal patterns at different time points (C1-C3). A color scale for log2 transformed data is shown. (B) A similar display is given for genes that display weaker signals in the mutant samples (down), they were also grouped into clusters (C4-C5). (C) For genes showing stronger signals in the mutant (up) significantly enriched GO terms and their identification numbers are given (left) together with the number of genes associated with the term (middle) and the number of genes observed versus expected. A color scale for enriched and depleted terms is show at the bottom.

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