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Table 1 Anthropometric, hormonal, metabolic and ultrasonographic characteristics of all patients with polycystic ovary syndrome (PCOS) and all controls.

From: The effects of obesity and polycystic ovary syndrome on serum lipocalin-2 levels: a cross-sectional study

 

Group I

(patients with PCOS)

(n = 200)

Group II

(controls)

(n = 50)

p

(adjusted for age and BMI)

Age (years)

24.5 ± 5.3

32.6 ± 4.7

NA

BMI (kg/m2)

27.0 ± 6.4

25.1 ± 4.0

NA

Waist (cm)

83.5 ± 14.9

80.8 ± 10.1

NS

FSH (mIU/ml)

6.4 ± 1.9

7.9 ± 2.8

0.007

LH (mIU/ml)

7.6 ± 5.0

5.9 ± 2.8

NS

Prolactin (ng/ml)

14.3 ± 6.9

12.2 ± 4.3

NS

Testosterone (ng/dl)

75.1 ± 30.1

32.9 ± 14.4

< 0.001

Δ4-A (ng/ml)

2.9 ± 1.0

1.7 ± 0.5

< 0.001

DHEA-S (ng/ml)

3106.0 ± 1300.8

1944.6 ± 811.8

< 0.001

FAI

7.64 ± 6.1

1.98 ± 1.16

0.002

17α-OHP (ng/ml)

1.1 ± 0.5

0.7 ± 0.3

0.010

SHBG (nmol/l)

47.1 ± 28.1

69.2 ± 33.7

NS

Glucose (mg/dl)

98.5 ± 21.5

97.0 ± 9.8

NS

Insulin (μIU/ml)

12.4 ± 9.1

9.2 ± 6.8

NS

Glucose/insulin

11.52 ± 6.7

14.86 ± 9.03

NS

HOMA-IR

3.22 ± 3.90

2.24 ± 1.71

NS

QUICKI

0.34 ± 0.03

0.35 ± 0.03

NS

Area under the OGTT curve

15143.9 ± 3134.1

14565.6 ± 3352.5

NS

Mean ovarian volume (cm3)

9.8 ± 4.9

5.3 ± 1.8

< 0.001

Mean number of ovarian follicles

10.8 ± 4.7

6.2 ± 1.9

< 0.001

Lipocalin (ng/ml)

65.4 ± 34.3

60.3 ± 26.0

NS

  1. NA, not applicable; NS, not significant; BMI, body mass index; FSH, follicle stimulating hormone; LH, luteinizing hormone; Δ4-A, Δ4-androstenedione; DHEA-S, dehydroepiandrosterone sulfate; FAI, free androgen index; 17α-OHP, 17α-hydroxyprogesterone; SHBG, sex hormone-binding globulin; OGTT, oral glucose tolerance test; HOMA-IR, homeostasis model assessment of insulin resistance; QUICKI, quantitative insulin sensitivity check index