| Group I (patients with PCOS) (n = 200) | Group II (controls) (n = 50) | p (adjusted for age and BMI) |
---|---|---|---|
Age (years) | 24.5 ± 5.3 | 32.6 ± 4.7 | NA |
BMI (kg/m2) | 27.0 ± 6.4 | 25.1 ± 4.0 | NA |
Waist (cm) | 83.5 ± 14.9 | 80.8 ± 10.1 | NS |
FSH (mIU/ml) | 6.4 ± 1.9 | 7.9 ± 2.8 | 0.007 |
LH (mIU/ml) | 7.6 ± 5.0 | 5.9 ± 2.8 | NS |
Prolactin (ng/ml) | 14.3 ± 6.9 | 12.2 ± 4.3 | NS |
Testosterone (ng/dl) | 75.1 ± 30.1 | 32.9 ± 14.4 | < 0.001 |
Δ4-A (ng/ml) | 2.9 ± 1.0 | 1.7 ± 0.5 | < 0.001 |
DHEA-S (ng/ml) | 3106.0 ± 1300.8 | 1944.6 ± 811.8 | < 0.001 |
FAI | 7.64 ± 6.1 | 1.98 ± 1.16 | 0.002 |
17α-OHP (ng/ml) | 1.1 ± 0.5 | 0.7 ± 0.3 | 0.010 |
SHBG (nmol/l) | 47.1 ± 28.1 | 69.2 ± 33.7 | NS |
Glucose (mg/dl) | 98.5 ± 21.5 | 97.0 ± 9.8 | NS |
Insulin (μIU/ml) | 12.4 ± 9.1 | 9.2 ± 6.8 | NS |
Glucose/insulin | 11.52 ± 6.7 | 14.86 ± 9.03 | NS |
HOMA-IR | 3.22 ± 3.90 | 2.24 ± 1.71 | NS |
QUICKI | 0.34 ± 0.03 | 0.35 ± 0.03 | NS |
Area under the OGTT curve | 15143.9 ± 3134.1 | 14565.6 ± 3352.5 | NS |
Mean ovarian volume (cm3) | 9.8 ± 4.9 | 5.3 ± 1.8 | < 0.001 |
Mean number of ovarian follicles | 10.8 ± 4.7 | 6.2 ± 1.9 | < 0.001 |
Lipocalin (ng/ml) | 65.4 ± 34.3 | 60.3 ± 26.0 | NS |