Figure 3

Cleaved caspase-3 expression in in-phase and out-of-phase endometrium. Histological sections were immunostained for cleaved caspase-3 expression (see text). Cleaved caspase-3 detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3. The percentage of cells expressing immunoreactivity for cleaved caspase-3 was established by analyzing 10 representative fields from each specimen. Out-of-phase endometrium shows a significantly higher percentage of cleaved caspase-3 positive cells than in-phase controls. ** p < 0.005 vs. Control.