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Table 2 Gestational age

From: Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor

Group

n

MMP-2

ng/mg CMP

TIMP-1

ng/mg CMP

MMP-8

ng/mg CMP

MMP-9

ng/mg CMP

IL-8

pg/mg CMP

Molar ratio

TIMP/MMP

Non pregnant

15

ND

6.3 (3.4-12)

0.020 (0.004-0.10)

0.32 (0.14-0.70)

0.031 (0.004-0.26)

40 (14-110)

Early pregnant

15

3.6 (2.4-5.3)

11 (9.1-14)

3.6 (2.5-5.2)

4.8 (3.5-6.6)

101 (72-139)

2.2 (1.6-3.1)

Term pregnant

15

0.54 (0.23-1.3)

1.2 (0.48-2.8)

6.6 (3.4-13)

7.5 (3.9-15)

213 (139-327)

0.20 (0.071-0.58)

ANOVA

P-value

45

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

  1. Concentrations and the molar TIMP/MMP ratios in the CMP-dists from non pregnant, early pregnant and term pregnant women. Protein concentrations are given as geometric mean (95% CI). ND: not detectable.