Table 4 Common pathway categories identified by GSEA of the 2 peritoneal endometriosis datasets
From: A cross-study gene set enrichment analysis identifies critical pathways in endometriosis
Pathway name | Classification | Genes |
|---|---|---|
Up-regulation | Â | Â |
Cell Communication | Cell Communication | 42 |
Focal adhesion | Cell Communication | 91 |
Regulation of actin cytoskeleton | Cell Motility | 61 |
PPAR signaling pathway | Endocrine System | 19 |
Calcium signaling pathway | Signal Transduction | 41 |
VEGF signaling pathway | Signal Transduction | 25 |
Cytokine-cytokine receptor interaction | Signaling Molecules and Interaction | 58 |
Neuroactive ligand-receptor interactio | Signaling Molecules and Interaction | 20 |
ECM-receptor interaction | Signaling Molecules and Interaction | 46 |
Cell adhesion molecules (CAMs) | Signaling Molecules and Interaction | 49 |
Complement and coagulation cascades | Immune System | 29 |
Hematopoietic cell lineage | Immune System | 29 |
Leukocyte transendothelial migration | Immune System | 44 |
Asthma | Immune Disorders | 7 |
Autoimmune thyroid disease | Immune Disorders | 12 |
Systemic lupus erythematosus | Immune Disorders | 20 |
Allograft rejection | Immune Disorders | 12 |
Graft-versus-host disease | Immune Disorders | 15 |
Arachidonic acid metabolism | Lipid Metabolism | 16 |
Type I diabetes mellitus | Metabolic Disorders | 15 |
Pancreatic cancer | Cancers | 24 |
Glioma | Cancers | 21 |
Down-regulation | Â | Â |
Sphingolipid metabolism | Lipid Metabolism | 13 |