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Table 4 Common pathway categories identified by GSEA of the 2 peritoneal endometriosis datasets

From: A cross-study gene set enrichment analysis identifies critical pathways in endometriosis

Pathway name Classification Genes
Up-regulation   
Cell Communication Cell Communication 42
Focal adhesion Cell Communication 91
Regulation of actin cytoskeleton Cell Motility 61
PPAR signaling pathway Endocrine System 19
Calcium signaling pathway Signal Transduction 41
VEGF signaling pathway Signal Transduction 25
Cytokine-cytokine receptor interaction Signaling Molecules and Interaction 58
Neuroactive ligand-receptor interactio Signaling Molecules and Interaction 20
ECM-receptor interaction Signaling Molecules and Interaction 46
Cell adhesion molecules (CAMs) Signaling Molecules and Interaction 49
Complement and coagulation cascades Immune System 29
Hematopoietic cell lineage Immune System 29
Leukocyte transendothelial migration Immune System 44
Asthma Immune Disorders 7
Autoimmune thyroid disease Immune Disorders 12
Systemic lupus erythematosus Immune Disorders 20
Allograft rejection Immune Disorders 12
Graft-versus-host disease Immune Disorders 15
Arachidonic acid metabolism Lipid Metabolism 16
Type I diabetes mellitus Metabolic Disorders 15
Pancreatic cancer Cancers 24
Glioma Cancers 21
Down-regulation   
Sphingolipid metabolism Lipid Metabolism 13
  1. Genes: Number of common genes included in the pathway.
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