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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues

Figure 3

Transcription factors activated transiently either at 30 min or 120 min by PRL treatment in decidua and ovary of PRLR-/-RS mice. Day 9 pseudopregnant PRLR-/-RS mice were injected with ergocryptine (200 μg, sc) for 6 hr followed by a single ip injection of either PRL (60 ug) or vehicle (control). Decidua and ovaries were obtained after 0, 30 and 120 min of PRL treatment. DNA binding activities of transcription factors were measured by Protein/DNA binding assay using nuclear extracts from ovary. (A) Transcription factors activated at 30 min by PRL treatment in the decidua (upper panel) and ovary (lower panel). (B) Transcription factors activated at 120 min by PRL treatment in the decidua (upper panel) and ovary (lower panel).

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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