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Table 2 Detection of total hCG, hyperglycosylated hCG and hyperglycosylated hCG free β in pregnancy serum [43, 4548].

From: New discoveries on the biology and detection of human chorionic gonadotropin

Gestation age (weeks since last menses) N Total hCG
Median (mIU/ml)
Hyperglycosylated hCG
(%) mean ± SD
Hyperglycosylated hCG free β (%) mean ± SD
3 weeks (implantation) n = 5 22 89 ± 24% 12 ± 22%
4 weeks (missing menses) n = 16 239 49 ± 21% 7.3 ± 5.9%
5 weeks n = 27 3,683 36 ± 13% 1.7 ± 0.75%
6 weeks n = 25 16,850 21 ± 14% 1.4 ± 0.63%
7 weeks n = 22 32,095 16 ± 13% 1.0 ± 0.24%
8 weeks n = 33 95,282 7.0 ± 5.4% 0.99 ± 0.51%
9 weeks n = 7 128,300 5.1 ± 4.4% 0.92 ± 0.35%
10 weeks n = 8 102,750 4.3 ± 3.1% 0.68 ± 0.47%
11 – 13 weeks n = 21 95,650 2.3 ± 1.5% 0.67 ± 0.33%
14 – 17 weeks n = 57 32,275 1.3 ± 0.61% 0.62 ± 0.26%
18 – 26 weeks n = 62 21,250 0.65 ± 0.60% 0.55 ± 0.42%
27 – 40 weeks n = 49 21,025 0.36 ± 0.16% 0.47 ± 0.19%
  1. Proportion hyperglycosylated hCG and hyperglycosylated hCG free β is the concentrations measured as a proportion of total hCG. SD is standard deviation. Gestational age is 3 day plus and 3 days minus specified week. So that data for 6 weeks pregnancy is 5 weeks 4 days to 6 weeks 3 days.