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Table 1 Comparison of androstenedione levels on different days after CYP17 shRNA 2# transduction, values are expressed as mean ± SD.

From: Study of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo

Lentivirus transduction day

CON

(ng/ml)

n = 6

NC

(ng/ml)

n = 6

2#

(ng/ml)

n = 6

Day 6

0.33 ± 0.028

0.16 ± 0.022

0.15 ± 0.045

Day 8

0.15 ± 0.029

0.081 ± 0.0068

0.047 ± 0.016 *

Day 10

0.32 ± 0.068

0.19 ± 0.078

0.085 ± 0.0094 *

  1. *ANOVA, P < 0.05, when compared with both CON and NC groups. CON: Blank Control; NC: Negative Control: 2#: CYP17 shRNA2#.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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