Table 3 Tissue content before perfusion (T0) and after 4 hours of perfusion (TE), accumulation (Atot) and net production (NP) as well as percent NP of T0 (% NP) of hCG and leptin
From: The impact of cocaine and heroin on the placental transfer of methadone
T0 | TE | Atot | NP | % NP | ||
|---|---|---|---|---|---|---|
Control perfusion (n = 6) | hCG [mU/g] | 6100 ± 4538 | 9028 ± 7205b | 11608 ± 7179 | 14536 ± 8956 | 299 ± 80 |
Leptin [pg/g] | 7944 ± 5189 | 10050 ± 7672c | 18122 ± 6824 | 20228 ± 8752 | 320 ± 136 | |
Perfusion with methadone (n = 6) | hCG [mU/g] | 3422 ± 2357 | 3996 ± 1908b | 6711 ± 3318 | 7285 ± 2868 | 269 ± 59 |
Leptin [pg/g] | 3673 ± 643 | 5590 ± 3431a | 14380 ± 4023 | 16298 ± 6737 | 480 ± 257 | |
Perfusion with methadone plus cocaine (n = 6) | hCG [mU/g] | 4530 ± 2202 | 5305 ± 4429b | 10539 ± 6563 | 11313 ± 8219 | 224 ± 116 |
Leptin [pg/g] | 2920 ± 544 | 4370 ± 2303b | 37744 ± 20897 | 39195 ± 22796 | 1200 ± 573 | |
Perfusion with methadone plus heroin (n = 6) | hCG [mU/g] | 3852 ± 1649 | 4336 ± 2088 | 5176 ± 2067 | 5660 ± 2647 | 169 ± 81 |
Leptin [pg/g] | 9856 ± 6146 | 5568 ± 2194a | 17949 ± 9578 | 13662 ± 7026 | 191 ± 573 |