Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line

Table 2 The incidence of BeWo syncytialization. The incidence of BeWo syncytialization was determined by scoring the absence of E-cadherin immunolocalization in groups of EGFP-fusion protein expressing cells. Data are from three independent experiments.

Experiment	BeWo + pEGFP-C3	BeWo + pEGFP-C3 -dn-ILK	BeWo + pEGFP-C3 - wt-ILK	BeWo + pEGFP-C3- ca-ILK
1	28/43	11/38	35/48	38/43
2	26/51	39/63	66/72	32/35
3	21/50	14/47	19/32	27/37
Avg. Incidence (% of 1.00 +/- SEM)	0.52 +/- 0.07	0.42 +/- 0.10	^a0.73 +/- 0.09	^b0.85 +/- 0.06

a: Syncytialization was significantly elevated in cells expressing wildtype (wt)-ILK versus dominant negative (dn)-ILK expressing cells (p < 0.05)
b: Syncytialization was significantly increased in BeWo cells expressing constitutively active (ca)-ILK vs cells containing pEGFP-C3 (empty vector) or dn-ILK (p < 0.05)

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