Table 3 Comparison of baseline data and cycle characteristics in ICSI cycles between pregnant and non-pregnant patients (clinical pregnancy).
From: Impact of GnRH ovarian stimulation protocols on intracytoplasmic sperm injection outcomes
Parameters | Pregnant | Non-Pregnant | Pvalue |
|---|---|---|---|
Number of cycles | 84 | 186 | |
Female age (years) | 31.4 ± 3.8 | 33.3 ± 4.8 | .006 |
Duration of infertility (years) | 3.9 ± 2.7 | 4.9 ± 3.5 | .018 |
Type of infertility | .202 | ||
Primary (never pregnant) | 75 (89.3) | 154 (82.8) | |
Secondary | 9 (10.7) | 32 (17.2) | |
Type of protocol | .233 | ||
Antagonist | 42 (50.0) | 109 (58.6) | |
Agonist | 42 (50.0) | 77 (41.4) | |
Number of attempts | 1.3 ± 0.8 | 1.6 ± 1.1 | .001 |
Basal FSH (mIU/ml) | 5.8 ± 1.9 | 6.6 ± 2.5 | .025 |
Basal E2 (pg/ml) | 54.8 ± 48.6 | 61.6 ± 63.0 | .367 |
BMI (Kg/m 2 ) | 23.1 ± 3.7 | 22.9 ± 3.4 | .846 |
Total ovarian volume (cm 3 ) | 13.4 ± 7.8 | 11.9 ± 5.7 | .252 |
Total number of antral follicles | 6.4 ± 4.1 | 6.0 ± 3.7 | .694 |
Initial FSH dose (IU) | 190.8 ± 53.3 | 212.2 ± 66.6 | .009 |
Total rFSH administered (IU) | 1961.3 ± 884.3 | 2210.7 ± 928.7 | .012 |
Duration of rFSH administration (days) | 9.8 ± 2.2 | 10.0 ± 2.6 | .503 |
Number of follicles ≥ 17 mm | 4.4 ± 2.1 | 4.3 ± 2.0 | .765 |
Number of retrieved oocytes | 10.2 ± 4.6 | 9.6 ± 5.8 | .070 |
Number of metaphase II oocytes | 8.7 ± 4.2 | 7.8 ± 4.7 | .031 |
Number of fertilized oocytes | 6.7 ± 3.5 | 5.7 ± 3.6 | .013 |
Number of cleaved embryos | 6.5 ± 3.4 | 5.5 ± 3.6 | .008 |
Number of transferred embryos | 2.2 ± 0.7 | 2.2 ± 0.7 | .958 |
Embryo transfer day | 1.000 | ||
Day 3 | 56 (66.7) | 124 (66.7) | |
Day 5 | 28 (33.3) | 62 (33.3) | |
Number of high quality embryos transferred | .802 | ||
1 | 12 (14.3) | 29 (17.6) | |
2 | 50 (59.5) | 94 (57.0) | |
3 | 22 (57.8) | 42 (25.5) | |
Endometrial thickness (mm) | 10.6 ± 1.6 | 10.2 ± 1.5 | .038 |
Serum E2 on hCG administration day (pg/ml) | 1885.3 ± 1009.8 | 1963.0 ± 1168.4 | .803 |