Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP

Table 3 Gene ontology categories significantly (p < 0.05) up-regulated and down-regulated in HeLa cells treated with NASP siRNA

UP REGULATED		DOWN REGULATED
P-value	GO category	P-value	GO category
1.10e-003	morphogenesis	1.51e-002	DNA packaging
2.10e-003	organogenesis	1.59e-002	cell adhesion receptor activity
7.68e-003	chromosome	1.67e-002	fatty acid metabolism
1.00e-002	nucleic acid binding	1.73e-002	muscle development
1.22e-002	chromatin	2.54e-002	carboxylic acid metabolism
1.36e-002	nucleic acid metabolism	2.95e-002	nucleosome assembly
1.69e-002	development	3.04e-002	chromatin architecture
2.02e-002	response to radiation	3.18e-002	nucleosome
2.11e-002	DNA packaging	3.33e-002	acyl-CoA dehydrogenase activity
3.19e-002	extracellular space	3.63e-002	chromosome organization
4.64e-002	intracellular transporter activity	3.90e-002	nuclear organization and biogenesis
4.84e-002	DNA binding	4.25e-002	DNA metabolism
4.96e-002	transporter activity	4.39e-002	chromatin assembly/disassembly
		4.73e-002	chromatin
		4.79e-002	development
		4.87e-002	chromosome