Table 2 Gene ontology categories significantly (p < 0.05) up-regulated and down-regulated in HeLa cells overexpressing NASP

1.56e-011

immune response

6.75e-003

transcription regulator activity

2.24e-011

response to biotic stimulus

2.68e-002

transcription factor complex

7.52e-011

defense response

3.85e-002

transcription factor activity

5.30e-009

response to external stimulus

4.21e-002

DNA binding

1.16e-008

cytokine activity

4.75e-002

nucleoplasm

5.89e-008

receptor binding

7.08e-007

response to stress

1.12e-006

response to pest/pathogen/parasite

1.62e-006

inflammatory response

1.81e-006

response to wounding

2.39e-006

innate immune response

8.28e-006

growth factor activity

9.48e-005

response to chemical substance

1.96e-004

regulation of cell proliferation

3.26e-004

apoptosis

3.31e-004

regulation of cell cycle

3.36e-004

programmed cell death

3.46e-004

chemokine activity

3.46e-004

chemokine receptor binding

4.59e-004

cell death

4.87e-004

death

5.27e-004

cell proliferation

7.09e-004

regulation of cellular process

7.72e-004

regulation of biological process

8.20e-004

cell cycle arrest

9.52e-004

regulation of cell proliferation

1.83e-003

cell-cell signaling

3.38e-003

response to virus

3.38e-003

anti-apoptosis

7.00e-003

cell communication

7.10e-003

signal transducer activity

9.37e-003

cell cycle

1.15e-002

response to abiotic stimulus

1.61e-002

nucleic acid binding

2.58e-002

transcription factor activity

3.10e-002

transcription regulator activity

3.27e-002

response to DNA damage stimulus

3.27e-002

regulation of apoptosis

3.31e-002

response to endogenous stimulus