Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 List of genes affected by NASP's altered expression

From: Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP

OVEREXPRESSION siRNA TREATMENT
Up-regulated Down-regulated Up-regulated Down regulated
Function/Gene Function/Gene Function/Gene Function/Gene
Transcription regulators:
ATF3, DDIT3, ETV5, FOSL1, IRF7, IRF9, RELB, STAT1
Transcription regulators:
EGR1, FOS, LMO1, NFE2
Transcription regulators:
HMGB2, E2F8
Transcription/translational regulators:
SRF, HOXA10, EIF2C4
  Transporters: AQP5 Enzymes:
ARL5A, CYP1B1, ME3, GSR, MANEA, GNG2, OGG1
 
Enzymes:
BIRC3, DDX60, IFIH1, OAS1, OAS3, OASL, PTGS2, RRAD
Others:
KR19, PLCXD3
Ion channel: KCNJ15 Enzymes:
ACADL, ACADSB, GLS, ARL1, CROT, DHTKD1, ENTPD7, FAAH2, GBP3, GATM, LIPH, SEPX1, ZDHHC2, UBE2N, SCCPDH
Cytokines:
CXCL1, CXCL2, CXCL3, TNF, IL11, IL1A, IL6, IL8
  Kinases:
PI4K2B, PDGFRB
Kinases: MAP2K1, RFK
Growth factors:
DKK1, EREG, GDF15
  Transmembrane receptors:
TNFRSF11B
Transmembrane receptors:
ITGB3, TLR3, ITGA5
    Growth factors: FGF2
Phosphatases:
DUSP5, NT5E
  G-protein coupled receptors:
F2RL1
Peptidases: CFI, CPA4
G-protein coupled receptors:
MRGPRD
  Transporters:
ATP6V1G3, FMN1, PNMA2, SMC1A, SAA1, SLC25A32
Transporters:
ATP11A, ATP2B4, FABP5, NUPL1, SEC13, SLC25A43
    Phosphatases: PPM1K
Others:
CLDN1, TNFAIP3, ZC3H12A, HRK, IFI27, IFI6, IFITM1, IGFL2, KRT34, LOC283454, PARP12, PARP9, PHLDA1, PPP1R15A, SAMD9L, STC2, GADD45A
  Others:
ARL6IP6, C14ORF167, CALB1, CALML4, CGA, CCDC5, CRYAB, FSTL1, FGFBP3, PRR16, SSU72, DTWD2, FST, ZMYM6, HAPLN1, TMSL8, MKX, HCG1815491, KIF5C, SYTL5, MFAP5, PSIP1, LOC100130476, RDM1, MEX3C, PHACTR2, NAP1L5, TMEM64, RASSF8, SLITRK6, ZBED2, MEFF2, TES, RBM17, TMEM80, UBE2E3
Others:
CPEB3, DCBLD2, DCP2, DENND1B, TMEM9B, TNC, ERLIN2, EVI5, GCOM1, HIST1H1C, HIST1H2BK, ZFYVE26, HIST2H2AA3, ZBTB41, NASP, CDCP1, KIAA0329, LOC285535, LONRF1, GPR137B, OSTM1, PCDH7, PPP1R3B, TM9SF4, PPP1R9A, PRRG4, SLAIN2, TUBB3, SHOC2, GLT8D3, CNN1, SPOCD1, DYX1C1, TTC39A, ACTA1, ACTA2, CCDC109A, CCDC126